Moss AJ, Zareba W, Hall WJ, et al Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction.
Merchant FM, Quest T, Leon AR, El-Chami MF Implantable cardioverter-defibrillators at end of battery life: opportunities for Risk (Re)-stratification in ICD recipients. These data represent an attempt to more fully characterize the spectrum of QoL and clinical outcomes after GE.Ĭopyright and License information: Journal of Geriatric Cardiology 2021. In terms of clinical outcomes, the incidence of appropriate shocks after GE among those with improvement in LVEF is very low, and most deaths post-procedure appear to be non-arrhythmic in origin. Patients undergoing ICD GE have significantly worse physical health compared to emotional/social well-being, which is associated with the presence of medical comorbidities. Four patients experienced appropriate ICD shocks after GE, three of whom had LVEF which remains impaired LVEF (i.e., < 35%) at the time of GE. Five patients died during follow-up and most deaths were adjudicated as non-arrhythmic in origin. Survival at 3 years post-GE was estimated at 80%. Overall SF-36 scores remained stable across all domains during follow-up. Mean follow-up was 1.6 ± 0.5 years after GE. Physical health scores were significantly worse among those with medical comorbidities including diabetes, chronic obstructive pulmonary disease and atrial fibrillation.
SF-36 scores were significantly worse in physical/general health domains compared to domains of emotional/social well-being ( P < 0.001 for each comparison). Mean age was 67.5 ± 14.3 years, left ventricle ejection fraction (LVEF) was 36.5% ± 15.0% and over 40% of the cohort had improved LVEF to > 35% at the time of GE. Serial assessments of health status were performed by administering the 36-Item Short Form Survey (SF-36). We prospectively followed patients undergoing first-time ICD GE. Little is known about health status and quality of life (QoL) after implantable cardioverter-defibrillator (ICD) generator exchange (GE).
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